The Relationship Between Triceps Skinfold and Overall Survival of Pancreas, Bile Duct, Gallbladder Cancer

Recruiting

• Conditions: Cholangiocarcinoma; Gallbladder Cancer; Pancreas Cancer
• Interventions: Other: Measurement of triceps skinfold thickness

• Registration Number: NCT03637569
• Lead Sponsor: Samsung Medical Center

Brief Summary

In this study, the investigators aim to demonstration of relationship between triceps skinfold thickness and overall survival of pancreatic cancer, cholangiocarcinoma and GB cancer.

Detailed Description

Cachexia is frequently seen in pancreatic cancer(70-80%) and associated with reduced survival, reduced treatment tolerance and reduction in QoL. In recent studies, low-normal BMI have worse outcome (overall mortality) in cardiovascular, malignant, chronic disease (So called "obesity paradox") BMI is simple method but hard to define body composition because BMI is based on only weight and height. Skinfold thickness is strongly associated with body fatness than BMI. In this study, the ivestigators aim to demonstration of relationship between triceps skinfold thickness and overall survival of pancreatic cancer, cholangiocarcinoma and GB cancer.

Study Timeline

• Study Start: 2018-04-01
• Study First Submitted: 2018-07-26
• Study First Submitted QC: 2018-08-16
• Study First Posted: 2018-08-20
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-24
• Last Update Posted: 2023-08-25
• Primary Completion: 2025-04-30
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

• Newly diagnosed pancreatic, bile duct or gallbladder cancer patients, undergoing therapeutic management (including surgery, chemotherapy or palliative care).
• Age above 18 years old

Exclusion Criteria

• Other malignant disease
• Underlying intestinal disease that cause absorprtion disorder
• Underlying psychiatric disorder such as eating disorder (bulimia, anorexia)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Cancer patients	Measurement of triceps skinfold thickness	Newly diagnosed pancreatic, bile duct or GB cancer patients at samsung medical center.

Primary Outcome Measures

Name	Time	Method
Overall survival	through study completion, an average of 2 year	The duration between diagnosis and death

Trial Locations

Locations (1)

Samsung Medical Center; 🇰🇷 Seoul, Korea, Republic of