Risk model to predict adverse outcomes after primary percutaneous coronary intervention (PCI)

Completed

• Conditions: Acute ST elevation myocardial infarction; Circulatory System; Acute myocardial infarction

• Registration Number: ISRCTN83474650
• Lead Sponsor: Clinical Center of Serbia (Serbia)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2008-09-30
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1750

Inclusion Criteria

1. Both males and females, 18 years of age or older
2. Chest discomfort persisting for more than 20 minutes
3. Presentation within 12 hours after the onset of symptoms
4. ST elevation in two contiguous leads of at least 0.2 mV in leads V2?V3 and/or of at least >0.1 mV in other leads, or new bundle branch block
5. Cardiac troponin exceeding upper reference limit at admission and/or 24 hours later

Exclusion Criteria

1. Refusal to give consent for invasive treatment
2. Contraindications for dual antiplatelet therapy or contrast agents (active or recent internal bleeding, history of bleeding after non-steroid anti-inflammatory agents, known bleeding diathesis, allergy, intracerebral mass or aneurysm, platelet count of <100,000/mm^3
3. Cardiogenic shock at admission
4. Noncardiac conditions that could limit life expectancy to less than 1 year or that might interfere with compliance with the protocol (active cancer, significant liver or renal disease [creatinine clearance <30 ml/min], significant psychiatric disorders)
5. Planned elective surgery necessitating interruption of treatment with thienopyridines during the first 6 months after enrolment

Study & Design

• Study Type: Observational
• Study Design: Not specified