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临床试验/CTRI/2025/01/079114
CTRI/2025/01/079114尚未招募不适用

The effect of Exercplay and Thoracic lymphatic pump technique on functional capacity and inflammatory parameters in children with bronchial asthma.

未提供1 个研究点 分布在 1 个国家目标入组 114 人开始时间: 2025年6月2日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
114
试验地点
1
主要终点
1. Sputum eosinophil count

研究概览

简要总结

Bronchial asthma (BA) is a chronic inflammatory respiratory condition characterized by bronchial hyperresponsiveness and airflow obstruction, often leading to symptoms like wheezing, shortness of breath, chest tightness, and cough. It not only affects respiratory health but can also result in reduced functional capacity, exertional dyspnea, fatigue, and activity limitations, impacting the quality of life. In children, asthma may reduce physical activity levels, with 5.5 million affected worldwide, constituting 7.5% of all children. Three key pathophysiological processes contribute to BA: bronchial inflammation, allergies, and bronchial hyperreactivity. These processes involve inflammatory cells, allergens, and excessive bronchoconstrictor responses. Current physiotherapy treatments aim to educate patients on asthma management and improve lung elasticity while addressing musculoskeletal dysfunctions. The thoracic lymphatic pump technique is a noninvasive approach for children with asthma, enhancing deep breathing and ventilation functions. Exercplay combines outdoor exercise and play to promote physical activity among children with controlled asthma. Physical fitness is associated with improved quality of life and reduced morbidity. These techniques have been used in various pulmonary conditions demonstrating promising effects on functional improvement and quality of life.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
7.00 Year(s) 至 12.00 Year(s)(—)
性别
All

入选标准

  • Children with mild to moderate Bronchial asthma assessed using pulmonary function test Asthmatic children with presence of sputum Participants will be recruited with reference to asthma diagnosis criterions of Global Initiative for Asthma including a history of variable respiratory symptoms and confirmed variable expiratory airflow limitation Children with well-controlled asthma, with no changes in asthma medication for less than 1 month and children who use inhalers bronchodilators will be included in the study.

排除标准

  • Children with severe and unstable asthma Subjects with poor cognition and perception & an inability to understand instructions necessary for assessment and treatment.
  • Participants with other cardiopulmonary, neurological and musculoskeletal disorders.
  • Exacerbation of asthma symptoms that required the use of systemic corticosteroids in the previous 4 week or during the study period.
  • Children with a history of thoracic surgery.
  • Children with Chest and Spinal deformities Red flag signs such as benign and malignant tumour.

结局指标

主要结局

1. Sputum eosinophil count

时间窗: 5 YEARS

2. Fractional exhaled nitric oxide (FeNO)

时间窗: 5 YEARS

次要结局

  • Six-minute walk test(Pediatric Asthma Quality of Life Questionnaire)

研究者

发起方
未提供
责任方
Principal Investigator
主要研究者

Preethi Gokulan

Saveetha college of physiotherapy, Saveetha University

研究点 (1)

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