“A Prospective study to assess the occurrence and factors causing trismus in patients with oral Cavity cancers Post Radiotherapy
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
研究概览
简要总结
This prospective, single-center observational cohort study conducted at SVIMS, Tirupati, aims to evaluate the occurrence of trismus in patients with oral cavity squamous cell carcinoma treated with radiotherapy, with or without concurrent chemotherapy. The study assesses clinical, tumor-related, and treatment-related factors contributing to post-radiotherapy trismus. Patients undergo detailed pretreatment evaluation, standardized radiotherapy planning using VMAT, and structured follow-up. Trismus is graded using CTCAE criteria, and statistical analysis is performed with SPSS to determine significant risk factors. Ethical approval, informed consent, and CTRI registration are ensured for regulatory compliance
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •1.Histo-pathologically proven squamous cell carcinoma [SCC] of oral and oropharyngeal cancers 2.Age : 18 -70 years .
- •3.Patients with eastern cooperative oncology group [ECOG] performance status of 0-2 4.Stage I to IV B SCC of oral cavity cancers [American joint committee on cancer : 8th edition
- •Patients treated with surgery.
排除标准
- •1.Cancer with distant metastasis.
- •2.Patient with ECOG performance status of 3-
- •3.Patients previously treated with radiotherapy to head & neck region.
研究者
Priya Bowjenku
Sri Venkateshwara Institute of Medical Sciences
