跳至主要内容
临床试验/CTRI/2026/03/105530
CTRI/2026/03/105530尚未招募不适用

“A Prospective study to assess the occurrence and factors causing trismus in patients with oral Cavity cancers Post Radiotherapy

Sri Venkateshwara Institute of Medical Sciences1 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2026年3月18日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
50
试验地点
1

研究概览

简要总结

This prospective, single-center observational cohort study conducted at SVIMS, Tirupati, aims to evaluate the occurrence of trismus in patients with oral cavity squamous cell carcinoma treated with radiotherapy, with or without concurrent chemotherapy. The study assesses clinical, tumor-related, and treatment-related factors contributing to post-radiotherapy trismus. Patients undergo detailed pretreatment evaluation, standardized radiotherapy planning using VMAT, and structured follow-up. Trismus is graded using CTCAE criteria, and statistical analysis is performed with SPSS to determine significant risk factors. Ethical approval, informed consent, and CTRI registration are ensured for regulatory compliance

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • 1.Histo-pathologically proven squamous cell carcinoma [SCC] of oral and oropharyngeal cancers 2.Age : 18 -70 years .
  • 3.Patients with eastern cooperative oncology group [ECOG] performance status of 0-2 4.Stage I to IV B SCC of oral cavity cancers [American joint committee on cancer : 8th edition
  • Patients treated with surgery.

排除标准

  • 1.Cancer with distant metastasis.
  • 2.Patient with ECOG performance status of 3-
  • 3.Patients previously treated with radiotherapy to head & neck region.

研究者

发起方
Sri Venkateshwara Institute of Medical Sciences
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Priya Bowjenku

Sri Venkateshwara Institute of Medical Sciences

研究点 (1)

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