Study of Tramadol Addiction Impact on Dental Anesthesia Success Among Algerian Males
试验速览
- 阶段
- 4 期
- 入组人数
- 400
- 试验地点
- 2
- 主要终点
- Anesthesia dose
研究概览
简要总结
Dental anesthesia is considered by far one of the main procedures in dentistry; the performance of a good dental anesthesia with a correct technique is paramount in controlling pain, facilitating the work of the dentist and gaining the confidence and cooperation of the patient
Tramadol is an FDA-approved medication for pain relief indicated mainly for moderate to severe pain, it is an opioid with 6 hours Half-Life and different dosages as 50mg, 100mg, 200mg and 300mg. Due to possible abuse and addiction potential, limitations to its use should be for pain that is refractive to other pain medication, such as non-opioid pain medication, unfortunately, the almost non-existent of censorship in Algeria and the disorderly framing made the obtain of tramadol as a medicine very easy which has led to a very alarming abuse of this drug
详细描述
Tramadol is an FDA-approved medication for pain relief indicated mainly for moderate to severe pain, it is an opioid with 6 hours Half-Life and different dosages as 50mg, 100mg, 200mg and 300mg. Due to possible abuse and addiction potential, limitations to its use should be for pain that is refractive to other pain medication, such as non-opioid pain medication, unfortunately, the almost non-existent of censorship in Algeria and the disorderly framing made the obtain of tramadol as a medicine very easy which has led to a very alarming abuse of this drug Meanwhile, apart from the systemic manifestations resulting from the abusive consumption of tramadol, it has become very clear that this opioid has a negative impact on the rapid and sufficient analgesic effect of dental anesthesia, it has been noticed that the anesthesia does not hold easily and the number of cartridges needed is increased, and therefore, a very particular attention must be attributed to the organization and control of its obtaining in order to limit its addiction in young people, an improvement of the care of patients must be offered according to the parameters necessary in the case of an addiction to tramadol
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •≥18 years
- •With no comorbid conditions (HTN, Diabetes & Epilepsy)
- •Tramadol addict (regular tramadol user)
排除标准
- •˂ 18 years
- •With comorbid conditions (HTN, Diabetes & Epilepsy)
- •≥ 65 years males
研究组 & 干预措施
Non- Tramadol
the control group represented by dental patients who are not a tramadol addict
干预措施: Dental anesthesia (Drug)
Tramadol
The study group with patients seeking dental service but also are tramadol addict.
干预措施: Dental anesthesia (Drug)
结局指标
主要结局
Anesthesia dose
时间窗: 3 months
Anesthesia carbols number through which both conc and dose needed in dental intervention in both arms
次要结局
未报告次要终点
研究者
Doaa Mohamed Salah ElDin Diab ELBohy
Assisstant professor
Future University in Egypt
