The effect of weekly text messaging to improve retention across the prevention of mother to child transmission of HIV program

Not Applicable

Completed

• Conditions: Retention in PMTCT program; Not Applicable

• Registration Number: ISRCTN98818734
• Lead Sponsor: Karolinska Institute (Sweden)

Brief Summary

2016 Protocol article in http://www.ncbi.nlm.nih.gov/pubmed/27401475 protocol 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34811384/ (added 24/11/2021) 2023 Results article in https://pubmed.ncbi.nlm.nih.gov/37296174/ (added 12/06/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-12-09
• Study Completion: 2017-12-30
• Last Update Posted: 26 June 2023

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 600

Inclusion Criteria

1. Woman aged 18 and above
2. Evidence of pregnancy as confirmed by urine test
3. Evidence of HIV infection (confirmed by a rapid test if newly detected and those known to be infected and referred from comprehensive care clinic) whether on ARVs or not
4. Resident of the PMTCT clinic catchment area (in urban and rural Kenya) and plans to remain residents from recruitment until 20 months after delivery
5. Willing to be followed-up from recruitment until 20 months after delivery
6. Own a mobile phone and/or have a phone in possession at the time of enrollment /or have access to a phone
7. Able or have someone in close contact that they trust to read and send/respond to a text message in Kiswahili
8. Willing to receive text messages from the PMTCT clinic
9. Able and willing to provide informed consent

Exclusion Criteria

Those not fulfilling the inclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Retention in PMTCT care defined as the proportion of HIV-exposed infants whose HIV status are confirmed at 18 months of age, measured as whether the infant was tested for HIV at 20- 24 months after birth (at or outside the selected clinics).

Secondary Outcome Measures

Name	Time	Method
1. Feasibility and Acceptability of WelTel SMS intervention on PMTCT participants <br>2. Effects of WelTel SMS on single PMTCT components <br>3. Cost against (i) effectiveness from a providers perspective and (ii) cost against the utility (differences in QUALYs between the 2 arms with the intervention arm having an improvement of 30%) from a patients perspective<br>4. A model framework for estimating cost-effectiveness of an m-health intervention to improve PMTCT outcomes, generalizable to other settings