Percutaneous Imaging-guided Cryoblation of the Anterior Abdominal Wall Endometriosis Scars

Recruiting

• Conditions: Endometriosis

• Registration Number: NCT06108167
• Lead Sponsor: University Hospital, Strasbourg, France

Brief Summary

Endometriosis is a common condition affecting 10% of women. It is characterized by the presence of ectopic endometrial cells. This pathology most frequently develops in the ovaries, utero-sacral ligaments and pelvic peritoneum, but also in the recto-sigmoid. Rarely, these lesions are found outside the pelvis, and even more exceptionally in the abdominal wall (in 0.03 to 1% of cases).

Cryotherapy has already been used for many years to treat soft tissue tumors (kidney and prostate tumors). It has also been successfully used by interventional radiologists to treat parietal desmoid tumors. After discussions with radiologists, given the similarity of location and extension of wall endometriosis lesions with desmoid tumours, the successes observed, and the scarcity of studies in the literature, it seemed appropriate to the investigators to study this new therapy.

The aim of this study was to investigate the efficacy of cryotherapy on parietal endometriosis lesions.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-05-05
• Status Verified: 2023-08
• Study First Submitted: 2023-08-28
• Study First Submitted QC: 2023-10-26
• Study First Posted: 2023-10-30
• Last Update Submitted: 2023-10-30
• Last Update Posted: 2023-11-02
• Primary Completion: 2023-11-05
• Study Completion: 2023-11-05

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 29

Inclusion Criteria

• Adult woman (≥18 years old) Having benefited from cryotherapy of an abdominal wall endometriosis nodule between January 6, 2020 and January 2, 2023.
• Subject not objecting to the reuse of their data for the purposes of this research

Exclusion Criteria

• Subject having expressed its opposition to the reuse of its data for scientific research purposes.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Efficacy of cryotherapy on parietal endometriosis lesions was assessed using the a visual analogue scale (VAS) ranging from 0 to 10.	Before and 6 months after the cryotherapy

Trial Locations

Locations (1)

Service de Gynécologie Obstétrique - CHU de Strasbourg - France; 🇫🇷 Strasbourg, France