Gel versus oral estrogen for endometrial preparation in freeze embryo transfer

Phase 4

Recruiting

• Conditions: A05.360.319.679.490; Female infertility; Male infertility; Assisted Reproductive Techniques; Estrogen Replacement Therapy; Endometrium; E02.875.800; E02.319.452.150

• Registration Number: RBR-8f837n
• Lead Sponsor: Irmandade da Santa Casa de Misericórdia de São Paulo

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-07-27
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

Women in the menacme with or older than 21 and with or younger than 38 years, when treated with their own eggs or women with or oldr than 21 and with or younger than 50 years when donor eggs or donor embryo.
One ou more fifth day (D5) or sixth day (D6) frozen blastocysts.
Body mass index (BMI) with or above 18 and with or lower than 35 Kg/m2.

Exclusion Criteria

Endocrine or metabolic abnormalities.
Serum progesterone concentrations higher than 1 ng / mL, on the day the study started, between the 2nd and 3rd day of the menstrual cycle.
Endometrial thickness higher then 5 mm at the beginning of the study, between the 2nd and 3rd day of the menstrual cycle.
Tumors: ovaries, breasts, adrenal, pituitary or hypothalamus
History of thrombosis or thrombophilia.
Alteration of renal or liver function.
Endometrial anatomical changes.
Hypersensitivity to the active substance or any of the excipients.
History of gastroplasty.

Study & Design

• Study Type: Intervention
• Study Design: Not specified