Prospective Evaluation of the Effect of Compliance With the Enhanced Recovery After Surgery Protocol on Postoperative Nutritional Risk and Prognostic Nutritional Index in Patients Undergoing Lung Cancer Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 2
- 主要终点
- Change in Nutritional Risk Screening 2002 Score
研究概览
简要总结
This prospective observational study will evaluate the association between ERAS protocol compliance and postoperative nutritional outcomes in 120 patients undergoing lung cancer surgery. ERAS compliance will be recorded, and patients will be classified as having high, moderate, or low compliance. NRS-2002 and PNI will be assessed before surgery and at postoperative 48 hours. Hospital stay and postoperative complications will also be evaluated.
详细描述
This single-center observational cohort study will include 120 patients aged 18-85 years undergoing elective lung cancer surgery. No intervention will be assigned. ERAS compliance will be categorized as high (≥80%), moderate (60-79%), or low (<60%). Changes in NRS-2002 and PNI, hospital stay, and postoperative complications will be evaluated using routine clinical data.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 85 years
- •Scheduled for elective lung cancer surgery under general anesthesia
- •ASA physical status I-III
- •Able to provide written informed consent
排除标准
- •Emergency surgery
- •Preoperative total parenteral nutrition
- •Advanced organ failure
- •Uncontrolled metabolic disease
- •Pregnancy or breastfeeding
- •Inability to provide informed consent
研究组 & 干预措施
High ERAS Compliance
Patients with an overall ERAS protocol compliance rate of 80% or greater.
干预措施: Routine ERAS Perioperative Care (Other)
Moderate ERAS Compliance
Patients with an overall ERAS protocol compliance rate between 60% and 79%.
干预措施: Routine ERAS Perioperative Care (Other)
Low ERAS Compliance
Patients with an overall ERAS protocol compliance rate below 60%.
干预措施: Routine ERAS Perioperative Care (Other)
结局指标
主要结局
Change in Nutritional Risk Screening 2002 Score
时间窗: From preoperative assessment to 48 hours after surgery
NRS-2002 will be assessed before surgery and at postoperative 48 hours. The score ranges from 0 to 7, with higher scores indicating greater nutritional risk. Change will be calculated as the postoperative score minus the preoperative score.
次要结局
- Change in Prognostic Nutritional Index(From preoperative assessment to 48 hours after surgery)
- Length of Hospital Stay(From surgery to hospital discharge, assessed up to 30 days)
- Postoperative Complications(From surgery to 30 days after surgery)
- ERAS Protocol Compliance(Perioperative/Periprocedural)
研究者
Emre Ulusoy
MD
Bursa City Hospital