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Clinical Trials/NCT02692352
NCT02692352
Completed
Not Applicable

Cognitive Rehabilitation of Executive Dysfunction - Goal Management Training in Patients With Acquired Brain Injury

Sunnaas Rehabilitation Hospital0 sites70 target enrollmentAugust 2012
ConditionsBrain Injuries

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Brain Injuries
Sponsor
Sunnaas Rehabilitation Hospital
Enrollment
70
Primary Endpoint
Executive functioning in daily life measured by self report questionnaire
Status
Completed
Last Updated
10 years ago

Overview

Brief Summary

The main objective of this study is to examine the effect of Goal Management Training for patients with executive difficulties after acquired brain injury in a randomized controlled trial. The effect on cognitive functioning will be examined, as will the relationship between treatment effects and lesion location and size. The effect of Goal Management training on regulating emotions, quality of life and coping will be examined. The generalizability of treatment effects across etiologies will be explored by comparing effects in three patient groups; traumatic brain injury, cerebrovascular accidents and resected brain tumors. Structural Magnetic Resonance Imaging (MRI) scans and measures of white matter connectivity will be used to establish detailed lesion descriptions. Functional MRI data will provide information on the neural underpinnings of treatment related change. A secondary objective is to expand the Goal Management Training protocol with increased focus on emotional regulation and adherence to homework assignment.

Registry
clinicaltrials.gov
Start Date
August 2012
End Date
June 2014
Last Updated
10 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Sunnaas Rehabilitation Hospital
Responsible Party
Principal Investigator
Principal Investigator

Sveinung Tornaas

Principal investigator

Sunnaas Rehabilitation Hospital

Eligibility Criteria

Inclusion Criteria

  • Traumatic Brain Injury, stroke and resected brain tumor patients with no concomitant diseases
  • Minimum 6 months post-injury/surgery
  • Reporting executive problems by structured interview or baseline assessment (cognitive performance measures)

Exclusion Criteria

  • Major psychiatric disorder or reported ongoing alcohol or substance abuse
  • Premorbid neurological disease or insult and/or comorbid neurological disease
  • Aphasia or other specified language problems causing potential communication problems
  • Impaired basic cognitive, linguistic, mnemonic, motor, or perceptual function that can interfere with the ability to engage with the training

Outcomes

Primary Outcomes

Executive functioning in daily life measured by self report questionnaire

Time Frame: one year

Behavior Rating Inventory Executive Functions Adult version

Executive functioning measured by neuropsychological assessment

Time Frame: one year

Conners Continous Performance Test

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