Cognitive Rehabilitation of Executive Dysfunction - Goal Management Training in Patients With Acquired Brain Injury
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 主要终点
- Executive functioning in daily life measured by self report questionnaire
研究概览
简要总结
The main objective of this study is to examine the effect of Goal Management Training for patients with executive difficulties after acquired brain injury in a randomized controlled trial. The effect on cognitive functioning will be examined, as will the relationship between treatment effects and lesion location and size. The effect of Goal Management training on regulating emotions, quality of life and coping will be examined. The generalizability of treatment effects across etiologies will be explored by comparing effects in three patient groups; traumatic brain injury, cerebrovascular accidents and resected brain tumors. Structural Magnetic Resonance Imaging (MRI) scans and measures of white matter connectivity will be used to establish detailed lesion descriptions. Functional MRI data will provide information on the neural underpinnings of treatment related change. A secondary objective is to expand the Goal Management Training protocol with increased focus on emotional regulation and adherence to homework assignment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 67 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Traumatic Brain Injury, stroke and resected brain tumor patients with no concomitant diseases
- •Minimum 6 months post-injury/surgery
- •Reporting executive problems by structured interview or baseline assessment (cognitive performance measures)
排除标准
- •Major psychiatric disorder or reported ongoing alcohol or substance abuse
- •Premorbid neurological disease or insult and/or comorbid neurological disease
- •Aphasia or other specified language problems causing potential communication problems
- •Impaired basic cognitive, linguistic, mnemonic, motor, or perceptual function that can interfere with the ability to engage with the training
结局指标
主要结局
Executive functioning in daily life measured by self report questionnaire
时间窗: one year
Behavior Rating Inventory Executive Functions Adult version
Executive functioning measured by neuropsychological assessment
时间窗: one year
Conners Continous Performance Test
次要结局
未报告次要终点
研究者
Sveinung Tornaas
Principal investigator
Sunnaas Rehabilitation Hospital
