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Clinical Trials/NCT04455295
NCT04455295
Active, not recruiting
Not Applicable

Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation

Arkansas Tech University1 site in 1 country55 target enrollmentSeptember 1, 2020
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Conditionsno ConditionElectroencephalographyPupil Diameter

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
no Condition
Sponsor
Arkansas Tech University
Enrollment
55
Locations
1
Primary Endpoint
Pupil Diameter
Status
Active, not recruiting
Last Updated
2 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

This study investigates the capacity of non-invasive vagus nerve stimulation, applied at the ear, to alter to measures of locus coeruleus output pupil diameter and EEG alpha power. Non-invasive alteration in locus coeruleus output is of interest in regard to basic science and has potential clinical implications in a number of conditions.

Registry
clinicaltrials.gov
Start Date
September 1, 2020
End Date
June 1, 2025
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Arkansas Tech University
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • •Healthy, 18 years of age or older.

Exclusion Criteria

  • •self-report of mood disorders, prescription and non-prescription drug use which includes stimulants including caffeine and nicotine

Outcomes

Primary Outcomes

Pupil Diameter

Time Frame: Within single one hour session

Pupil diameter is measured via camera.

EEG Alpha power.

Time Frame: Within single one hour session

Alpha power will be determined from EEG.

Study Sites (1)

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