Quality of the Management of Diabetes in Elderly People With Dementia in France. Longitudinal Study in the French National Health System Database During 2010-2015
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 87,816
- 试验地点
- 1
- 主要终点
- Diabetes control
研究概览
简要总结
Along with population ageing, the association of chronic conditions such as Alzheimer's Disease and Related Syndromes (ADRS) and diabetes mellitus is increasing in clinical practice. According to ADRS severity, guidelines of diabetes care may be adapted for a personalized monitoring and treatment. The consequences on diabetes complications are not known and can also threaten dementia progression. Based on a nationwide healthcare reimbursement database, the present study aimed to compare diabetes care and the incidence of acute complications between patients with or without ADRS, in a longitudinal perspective focusing on the pivotal period of ADRS identification by the healthcare system.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •individuals with a first ADRS criterion in 2011 or 2012,
- •prevalent diabetes mellitus, defined by a LTD with ICD-10 codes of diabetes mellitus ("E10-E14").
- •at least one reimbursement in the year preceding inclusion.
排除标准
- 未提供
结局指标
主要结局
Diabetes control
时间窗: one year
Given the absence of consensual guidelines describing the frequency of diabetes monitoring among elderly subjects, we defined a conservative minimal threshold as follows: ambulatory biological monitoring : * ≥ 1 annual HbA1c determination (primary endpoint) * ≥ 2 annual HbA1c determination * ≥ 1 annual lipid profile (≥ 1 annual LDL cholesterol, ≥ 1 annual triglyceride)
次要结局
- Ocular Diabetes complications(one year)
- diabetic coma(one year)
- diabetic nephropathy(one year)
- hospitalization for any of the 5 previous diabetes-related cause(one year)
- Hypoglycemia(one year)
- ketoacidosis without coma(one year)
- diabetic neuropathy(one year)
- hospitalization for falls and femoral fracture(one year)