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Ultrasound of the Inferior Vena Cava in the Prevention of Hypotension After Induction of General Anesthesia

Not yet recruiting
Conditions
Elderly Patients Undergoing Elective Non-cardiac Surgery
Interventions
Diagnostic Test: Multidimensional ultrasound of the inferior vena cava
Registration Number
NCT06530901
Lead Sponsor
Zhuan Zhang
Brief Summary

Based on the preoperative ultrasound detection of various parametric indicators of the inferior vena cava cross-section, including the ratio of the inferior vena cava's long and short axes, cross-sectional area and circumference during two-dimensional and three-dimensional imaging, as well as the changes in respiratory variability of each parameter, we explored the predictive value of IVC ultrasound indicator parameters on hypotension after induction of general anesthesia in elderly patients undergoing elective non-cardiac surgery, screened the sensitive indicators, and calculated the cut-off values.

Detailed Description

Not available

Recruitment & Eligibility

Status
NOT_YET_RECRUITING
Sex
All
Target Recruitment
100
Inclusion Criteria
  • Elderly patients undergoing elective non-cardiac surgery under general anesthesia;
  • Age 65-85 years old;
  • Body mass index (BMI) 18-28 kg/m2;
  • American society of anesthesiologists (ASA) class I-III.
Exclusion Criteria
  • Patient refusal or lack of cooperation;
  • Inability to communicate properly;
  • Severe sinus bradycardia, pacemaker implantation, atrioventricular block, and atrial fibrillation;
  • Presence of severe hepatic and renal function abnormalities;
  • Preoperative cardiac ultrasound suggesting LVEF <50%;
  • Tricuspid valve displacement <16 mm by preoperative cardiac ultrasound;
  • Chronic obstructive pulmonary disease;
  • Pulmonary hypertension;
  • Administration of drugs that inhibit the renin-angiotensin-aldosterone system;
  • Possibility of a difficult airway.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Elderly patients undergoing elective noncardiac surgery under general anesthesiaMultidimensional ultrasound of the inferior vena cava-
Primary Outcome Measures
NameTimeMethod
Changes in the level of Systolic Blood PressureBaseline (before induction), 10 min after induction

The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction

Multidimensional ultrasound of the inferior vena cavaBaseline (before induction)

The outcome above should be measured at the time before induction

Changes in the level of Mean Arterial PressureBaseline (before induction), 10 min after induction

The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction

Secondary Outcome Measures
NameTimeMethod
Changes in the level of Heart RateBaseline (before induction), 10 min after induction

The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction

Changes in the level of Diastolic Blood PressureBaseline (before induction), 10 min after induction

The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction

Trial Locations

Locations (1)

the Affiliated Hospital of Yangzhou University, Yangzhou University

🇨🇳

Yangzhou, Jiangsu, China

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