Multidimensional Ultrasound of the Inferior Vena Cava in the Prevention of Hypotension After Induction of General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Changes in the level of Systolic Blood Pressure
研究概览
简要总结
Based on the preoperative ultrasound detection of various parametric indicators of the inferior vena cava cross-section, including the ratio of the inferior vena cava's long and short axes, cross-sectional area and circumference during two-dimensional and three-dimensional imaging, as well as the changes in respiratory variability of each parameter, we explored the predictive value of IVC ultrasound indicator parameters on hypotension after induction of general anesthesia in elderly patients undergoing elective non-cardiac surgery, screened the sensitive indicators, and calculated the cut-off values.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 85 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Elderly patients undergoing elective non-cardiac surgery under general anesthesia;
- •Age 65-85 years old;
- •Body mass index (BMI) 18-28 kg/m2;
- •American society of anesthesiologists (ASA) class I-III.
排除标准
- •Patient refusal or lack of cooperation;
- •Inability to communicate properly;
- •Severe sinus bradycardia, pacemaker implantation, atrioventricular block, and atrial fibrillation;
- •Presence of severe hepatic and renal function abnormalities;
- •Preoperative cardiac ultrasound suggesting LVEF <50%;
- •Tricuspid valve displacement <16 mm by preoperative cardiac ultrasound;
- •Chronic obstructive pulmonary disease;
- •Pulmonary hypertension;
- •Administration of drugs that inhibit the renin-angiotensin-aldosterone system;
- •Possibility of a difficult airway.
结局指标
主要结局
Changes in the level of Systolic Blood Pressure
时间窗: Baseline (before induction), 10 min after induction
The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction
Multidimensional ultrasound of the inferior vena cava
时间窗: Baseline (before induction)
The outcome above should be measured at the time before induction
Changes in the level of Mean Arterial Pressure
时间窗: Baseline (before induction), 10 min after induction
The outcome above should be measured at the time before induction, 1 min after induction, 2 min after induction, 3 min after induction, 4 min after induction, 5 min after induction,10 min after induction
次要结局
- Changes in the level of Heart Rate(Baseline (before induction), 10 min after induction)
- Changes in the level of Diastolic Blood Pressure(Baseline (before induction), 10 min after induction)
研究者
Zhuan Zhang
Doctor
Yangzhou University