JPRN-jRCT1051180028已完成2 期
Induction Chemotherapy and Adjuvant Thoracic Radiation in Resectable Stage N2-3A/3B Non-small Cell Lung Cancer - ICAT in N2-3A/3B NSCLC
Inoue Masayoshi0 个研究点目标入组 1 人开始时间: 2019年1月17日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 1
研究概览
简要总结
The feasibility of Trimodality using preoperative chemotherapy, radical resection, and postoperative radiation is still unknown.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 < 75age old（—）
- 性别
- All
入选标准
- •1. c-stage 3A/3B with pathologically diagnosed N2 without chest wall invasion
- •2.Resectable following induction chemotherapy
- •3.Normal pulmonary function within 56days before IC
- •4.No previous chemotherapy or thoracic radiation
- •5.age 20-75 years at IC
- •6.ECOG Performance Status0-1
- •7.Normal bone marrow, liver, and renal function below within 28days before IC
- •8.Written informed consent was obtained
排除标准
- •1.Unresectable extra-nodal mediastinal lymph node in CT
- •2.Contraindication for CBDCA or nab-PTX
- •3.Past history of severe drug allergy
- •4.Pulmonary dysfunction
- •5.Myocardial infarction within 180 days before IC
- •6.Interstitial pneumonia or pulmonary fibrosis detected in CT 56days before IC
- •7.Medication with PSL more than 10mg/day 90days before IC
- •8.Clinically relevant heart disease
- •9.Clinically relevant psychological disorder
- •10.Uncontrollable DM
- •11.Clinically relevant infection disease
- •12.Other clinically relevant comorbidity
- •13.Active double cancer
- •14.Pregnant, lactating, possibly pregnant
- •15.Inappropriate by investigator
研究者
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