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Clinical Trials/NCT06170034
NCT06170034
Completed
Not Applicable

Post-emergency Management of Patients with Transient Ischemic Attack

Centre Hospitalier Henri Duffaut - Avignon1 site in 1 country49 target enrollmentNovember 16, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Transient Ischemic Attack
Sponsor
Centre Hospitalier Henri Duffaut - Avignon
Enrollment
49
Locations
1
Primary Endpoint
Assess time between arrival in the emergency department for suspected TIA patients and MRI.
Status
Completed
Last Updated
last year

Overview

Brief Summary

A transient ischemic attack (TIA) is a momentary neurological dysfunction due to a brief cessation of blood flow to a region of the brain, resulting in typical signs of stroke (hemiplegia, aphasia, dysarthria), but whose clinical symptoms typically last less than an hour, with no visible lesion on imaging. This diagnosis remains difficult and is essentially based on the clinical judgment of the physician.

Because a TIA can be a "pre-alarm" for stroke in 20-30% of cases, it needs to be treated appropriately and as early as possible in the emergency department. Stroke rates after untreated TIA are 5% within 48 hours, 10% within one month and 20% within one year. This risk is calculated using the ABCD² score which is based on the patient's risk factors and the clinical manifestations of TIA. Patients with a score ≥ 3 should be hospitalized as soon as possible for a complete medical evaluation. However, this score has not been scientifically validated, and several specialists agree that all TIAs should be evaluated immediately. Preventing stroke is a major public health issue because it is a serious, disabling and sometimes fatal disease. Given the seriousness of the progression from TIA to stroke, the French National Authority for Health has issued a series of management recommendations. However, in practice, these guidelines remain complicated to follow and patients management may vary and be more or less effective.

Therefore, the aim of this study is to highlight the differences in how inpatients and outpatients are managed. Following these observations, solutions will be sought to make the care and management of these patients more efficient and more in line with recommendations.

Registry
clinicaltrials.gov
Start Date
November 16, 2023
End Date
June 16, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Centre Hospitalier Henri Duffaut - Avignon
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient over 18 years old.
  • Consultation in the emergency department.
  • Suspected TIA diagnosed by emergency physician.
  • Duration of TIA symptoms \<1 hour.

Exclusion Criteria

  • Validation MRI performed prior to suspected TIA.
  • Patient hospitalized for a condition other than TIA, including stroke.
  • Patient referred to another hospital for further examination.
  • Pregnant women.
  • Patient unable to understand and answer a questionnaire.
  • Patient under legal protection.

Outcomes

Primary Outcomes

Assess time between arrival in the emergency department for suspected TIA patients and MRI.

Time Frame: Baseline

Secondary Outcomes

  • Time between arrival in the emergency department and MRI by ABCD² score.(Baseline)
  • Percentage of patients with complete TIA management by departments.(Baseline)
  • Time between arrival in the emergency department and MRI by departments.(Baseline)
  • Hospitalization times according to care units(Baseline)
  • Percentage of patients with secondary event, according to complete TIA management(Baseline)
  • Number of outpatients without complete TIA management one month after TIA.(At 1 month follow-up)
  • Hospitalization times according to complete TIA management(Baseline)
  • Patient satisfaction with a short questionnaire(At 1 month follow-up)

Study Sites (1)

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