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临床试验/NCT01022788
NCT01022788已完成不适用

Improving Newborn Survival in Rural Southern Tanzania: a Study to Evaluate the Impact and Cost of a Scaleable Package of Interventions at Community Level With Health System Strengthening

London School of Hygiene and Tropical Medicine1 个研究点 分布在 1 个国家目标入组 47,688 人开始时间: 2010年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
47,688
试验地点
1
主要终点
Newborn survival (to 28 days)

研究概览

简要总结

This study will develop, implement and evaluate the effectiveness and cost of interventions at community level (focussed on a community-based health worker) and of health system strengthening on newborn survival in rural southern Tanzania.

Objectives

  1. To develop and document a community-based package for improved newborn care, focussed around interpersonal communication through home visits in pregnancy and the early neonatal period .
  2. To develop and document a quality improvement package for antenatal, intrapartum and postnatal care in health facilities.
  3. To implement these strategies for improved newborn survival in such a way as to be both sustainable and scaleable at national level.
  4. To monitor understanding of, and attitudes related to, neonatal care and survival from both health provider and community perspectives in areas with and without the interventions.
  5. To measure incremental costs and cost savings to the health sector and society associated with the interventions, and to predict the cost of integrating the programme into routine health service provision and of scaling-up
  6. To strengthen Tanzania's capacity to develop, implement and evaluate interventions to improve neonatal survival.
  7. To estimate the effect of the interventions on newborn survival and household behaviours related to newborn health.

Study design & methods. The interventions will be implemented in parts of Lindi and Mtwara regions. The health system quality improvement package will be implemented throughout the area and evaluated using a before-after comparison. The community intervention will be implemented initially in a randomly-chosen half of all wards (a ward is an administrative sub-area of a district). Implementation will be led by existing front-line health staff. Evaluation will include a health facility survey and a household survey to assess contacts with the agents of change, key behaviours and newborn survival in the community.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Health Services Research
盲法
None

入排标准

年龄范围
— 至 49 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Pregnant women living in the study area

排除标准

  • Unwilling to participate

结局指标

主要结局

Newborn survival (to 28 days)

时间窗: July 2010 to June 2013

次要结局

  • Household behaviours for essential newborn care(July 2010 to June 2013)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Joanna Schellenberg

Professor of Epidemiology and International Health

London School of Hygiene and Tropical Medicine

研究点 (1)

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