To study the role of Virechana and Bhringrajadi Lepa on Vitiligo in children

Phase 3

Completed

Conditions: Vitiligo. Ayurveda Condition: SVITRAH,

Registration Number: CTRI/2022/05/042423

Lead Sponsor: National Institute of Ayurveda Jaipur Rajasthan

Brief Summary: Recently rapidly increasing incidences of *Shwitra* is a challenge for medical world. Vitiligo is the pigmentary disorder of certain hereditary and acquired and autoimmune causes and characterized by depigmented or hypopigmented patches that results from absence or depleted in melanocytes. Pathogenesis of vitiligo points towards autoimmune hypothesis1 and disease may start at any age with increased incidences in first and second decade of life. Based on some dermatological out patient records the incidences are roughly estimated to be between 3-4% in India. However, vitiligo affects the estimated 1-2%of world population which is quite significant2. Present study has been designed to study the role of *Samshodhan Karma* followed by *BhringrajadiLepa*, externally, over the discoloured patches in children with subsequent exposure to sunlight. *BhringrajadiLepa* has been quoted in the classics (Bhrihad Nighantu Ratnakar by Khemraj Shri Krishna Das, Chapter-*Tvagadosha*,

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: All

Target Recruitment: 30

Inclusion Criteria

1.Patient of either sex between age group of 05 -15 years 2.Children diagnosed as vitiligo as per contemporary medical science or Shwitra as per clinical features mentioned in Ayurvedic texts.

Exclusion Criteria

1.Children below 05 and above 15 years of age.
2.Children with Albinism will be excluded.
3.White anesthetic spots, which are characteristic of leprosy will be excluded.
4.Old refractory cases not responding after extensive use of modern medicine will be also excluded.
5.One year old vitiligo patch will be excluded.
6.Patches in genital and lip area will be excluded.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary Outcome Measures- VASI Score	baseline, 15th day

Secondary Outcome Measures

Name	Time	Method
Cosmetic concern of the patient regarding depigmentation of the skin	baseline, 15th day

Trial Locations

Locations (1): National Institute of Ayurveda, Jaipur
🇮🇳
Jaipur, RAJASTHAN, India
National Institute of Ayurveda, Jaipur
🇮🇳Jaipur, RAJASTHAN, India
DR YOGESH CHOUKIKAR
Principal investigator
8109428870
dryogeshchoukikar@gmail.com