The effect of exercise on brain blood flow and metabolism in stroke survivors
- Conditions
- StrokeCirculatory System
- Registration Number
- ISRCTN41026907
- Lead Sponsor
- Royal Victoria Infirmary, Newcastle (UK)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 42
1. Over 50 years old
2. Diagnosed with a stroke by a stroke physician through computer tomography or magnetic resonance imaging and clinical characteristics at least six months previously
3. Participants are all able to walk for six minutes independently allowing for rests with or without a stick
4. Lives at home
5. Completed all conventional physiotherapy offered by the National Health Service (NHS)
1. The absolute and relative contraindications to exercise testing as stated by the American Heart Association (Fletcher et al., 2001)
2. Other neurological or medical conditions in addition to stroke which would prevent individuals from participating
3. A diagnosis of diabetes, the presence of pain on walking (>5 on a visual analogue scale of pain)
4. Untreated major depression
5. Cognitive or speech problems limiting understanding of the study (participants were excluded if their Mini Mental Scale Examination (MMSE) was under 25 and if they were unable to follow two stage commands) (Folstein et al. 1975)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Glucose control (frequently sampled oral glucose tolerance test)<br>2. Cerebral blood flow via magnetic resonance imaging (MRI)
- Secondary Outcome Measures
Name Time Method 1. Cardiorespiratory fitness<br>2. Body composition<br>3. Stroke impairment<br>4. Cognition<br>5. Endurance speed and balance<br>6. Physical activity<br>7. Quality of life