Evaluation of the Use of Arterial Pulse Waveform Contour Analysis for Early Goal Directed Therapy in Patients Undergoing Major Abdominal Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 46
- 试验地点
- 2
- 主要终点
- Length of Postoperative Hospital Stay
研究概览
简要总结
This study evaluates whether using information from a special arterial blood pressure monitor to guide how much fluid is given during surgery changes how long a patient stays in the hospital after the surgery. There is scientific evidence from using similar information from different devices that this technique might allow us to do a better job giving fluids during surgery and that this may be associated with shorter hospital stay after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients requiring elective or semi-elective major abdominal surgery will be assessed for eligibility.
排除标准
- •Age under 18 years old,
- •Coagulopathy,
- •Significant renal/hepatic dysfunction (creatine >50% or liver enzymes > 50% of normal values),
- •Congestive heart failure,
- •Cardiac arrhythmias producing irregular rhythms, and
- •Patient choice.
研究组 & 干预措施
Standard fluid management
standard intraoperative fluid management as determined by usual monitoring and decision making applied by anesthesiology team
Goal directed therapy
Intraoperative fluid management guided by stroke volume variation determined by arterial pressure pulse wave contour analysis
干预措施: Vigileo (Device)
结局指标
主要结局
Length of Postoperative Hospital Stay
时间窗: within one month
time in days from end of surgery to hospital discharge
次要结局
- Quality of Recovery Score on Postoperative Day 2(Postoperative day 2)
- Quality of Recovery Score on Postoperative Day 4(Postoperative day 4)
研究者
Davinder Ramsingh, MD
MD
Loma Linda University