NCT04396158Unknown不适用
Effect of Radioiodine Therapy on Ovarian Reserve in Female Patients With Differentiated Thyroid Cancer
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 38
- 主要终点
- Level of anti-Müllerian (AMH) hormone
研究概览
简要总结
Thyroid carcinoma is the most common endocrine malignancy. Surgery is the standard therapeutic approach for patients with differentiated thyroid carcinoma (DTC), followed by radioiodine (RAI) therapy if indicated. For women with DTC, the effects of RAI therapy on gonadal and reproductive function are an important consideration. This study aimed to evaluate the effects of RAI therapy on ovarian function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 15 Years 至 45 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Female patient in childbearing period.
- •Female patient with differentiated thyroid carcinoma.
- •Underwent thyroidectomy.
- •Candidate for radioactive iodine therapy.
排除标准
- •• Male patients.
- •Postmenopausal female patients.
- •Female patients with undifferentiated thyroid carcinoma.
- •Pregnant female patients.
- •Lactating female patients.
结局指标
主要结局
Level of anti-Müllerian (AMH) hormone
时间窗: 6 months
Level of anti-Müllerian (AMH) hormone in female patients before and after radioactive iodine therapy.
次要结局
未报告次要终点
研究者
Hebat Allah Ahmed Askar
Lecturer of nuclear medicine
Assiut University
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