Stroke Recovery Research Based on EEG-fMRI
- Conditions
- Motor Neuropathy
- Registration Number
- NCT05427422
- Lead Sponsor
- Health Science Center of Xi'an Jiaotong University
- Brief Summary
This study is aimed to investigate the post-stroke motor recovery of patients with ischemic stroke based on their neural features extracted from EEG-fMRI data.
- Detailed Description
A group of patients with ischemic stroke and age/gender matched healthy controls would be enrolled in this study. Their features of neural activities based on EEG-fMRI fusion scan would be extracted to investigate the mechanisms of motor recovery after stroke. Particularly, the correlations of their features of neural networks or local activities to their motor function (defined as their Fugl-Meyer scores) at enrollment and their recovery time courses consisted of Fugl-Meyer scores in follow-up time points.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 111
- Age above 18 and below 75 years
- Motor impairment in National Institutes of Health Stroke Scale
- 7-14 days since stroke attack
- First-ever ischemic stroke
- Motor impairment induced by non-stroke aetiology
- Claustrophobia; recognition disorder
- History of other severe central nervous system diseases
- Any signs unfit for MRI/EEG scan
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fugl-Meyer scores (T1) 6 weeks since stroke a scale widely used to evaluate one's motor impairment
Fugl-Meyer scores (T0) 7-14 days since stroke a scale widely used to evaluate one's motor impairment
Fugl-Meyer scores (T2) 12 weeks since stroke a scale widely used to evaluate one's motor impairment
Fugl-Meyer scores (T3) 72 weeks since stroke a scale widely used to evaluate one's motor impairment
- Secondary Outcome Measures
Name Time Method Neuroimage features based on EEG-fMRI (T3) 72 weeks since stroke Neuroimage features extracted from EEG-fMRI data
Neuroimage features based on EEG-fMRI (T0) 7-14 days since stroke Neuroimage features extracted from EEG-fMRI data
Neuroimage features based on EEG-fMRI (T1) 6 weeks since stroke Neuroimage features extracted from EEG-fMRI data
Neuroimage features based on EEG-fMRI (T2) 12 weeks since stroke Neuroimage features extracted from EEG-fMRI data
Trial Locations
- Locations (1)
Xi'an Daxing Hospital
🇨🇳Xi'an, Shanxi, China
Xi'an Daxing Hospital🇨🇳Xi'an, Shanxi, China