A Comparison of Remifentanil Patient-Controlled Analgesia vs. Oral Morphine Analgesia for Dressing Changes in Burns Patients.
Phase 1
- Conditions
- Pain experienced by patients with pre-existing burns presenting to the burns outpatients unit requiring two or more dressing changes
- Registration Number
- EUCTR2008-007322-19-GB
- Lead Sponsor
- Queen Victoria Hospital NHS Foundation Trust
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 58
Inclusion Criteria
•Outpatients requiring two or more dressing changes for burns who would normally be considered appropriate for oral morphine analgesia.
•ASA 1 and 2 patients over the age of 18 years
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
•Patients unable to use the hand control of the PCA device
•Patients who are unable to give full consent or do not agree to participate in the trial
•Hypersensitivity or history of serious adverse reactions to remifentanil or morphine
•Surgical or anaesthetic objections
•Pregnancy
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: To determine whether remifentanil PCA or oral morphine provides more effective analgesia for out-patient dressing changes in the burns unit.<br>;Secondary Objective: To determine if burns patients prefer traditional analgesia or remifentanil analgesia for dressing changes ;Primary end point(s): Maximum visual analogue scale (VAS) pain score during the dressing change procedure.<br>
- Secondary Outcome Measures
Name Time Method