Genetic Polymorphism as Moderator of the Effect of an Acute Bout of Exercise on Cognitive Function

Not Applicable

• Conditions: Executive Function
• Interventions: Other: Cognitive function after exercise test; Genetic: Blood sample analysis

• Registration Number: NCT01718405
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

Studies have shown that an acute bout of aerobic exercise positively effects cognition, mainly executive functioning; however the effect is not observed among all people and it is not clear whether only aerobic exercise can produce this effect or possibly also resistant exercise. The main purpose of our study is to examine whether genetic variation is a moderator of this effect and whether resistant exercise is comparable to aerobic exercise in improving cognition following a single bout of exercise.

Detailed Description

Not available

Study Timeline

• Status Verified: 2012-10
• Study First Submitted: 2012-10-10
• Study First Submitted QC: 2012-10-29
• Last Update Submitted: 2012-10-29
• Study First Posted: 2012-10-31
• Last Update Posted: 2012-10-31
• Study Start: 2012-11
• Primary Completion: 2015-11
• Study Completion: 2017-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• Physical Education Students
• Able to sign consent form

Exclusion Criteria

• Competitive athletes
• Smokers
• Neurologic or psychologic orders
• Chronic diseases
• Head Injuries
• Hospitalization in the previous 3 months
• Pregnant

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Exercise Group	Cognitive function after exercise test	Each individual subject will give a blood sample for genetic analysis and undertake an exercise session and a rest session as a control. Cognitive function will be tested before and after each session.
Exercise Group	Blood sample analysis	Each individual subject will give a blood sample for genetic analysis and undertake an exercise session and a rest session as a control. Cognitive function will be tested before and after each session.

Primary Outcome Measures

Name	Time	Method
Cognitive Functioning After Exercise	Five minutes	Computerized battery of tests evaluating cognitive functioning

Trial Locations

Locations (1)

Wingate Institute; 🇮🇱 Netanya, Israel