Cognitive, Psychological, and Physical Functioning in Long-COVID Patients With Different Levels of Fatigue.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 69
- 试验地点
- 1
- 主要终点
- Fatigue severity
研究概览
简要总结
Post COVID-19 usually occurs 3 months from the onset of COVID-19 with symptoms that last for at least 2 months and cannot be explained by an alternative diagnosis. Patients report a range of disabling symptoms such as fatigue, shortness of breath, cognitive impairment, memory loss and mental health and employment issues. This clinical heterogeneity complicates the identification of the appropriate needs and care.
The aim of this cross-sectional study is to identify subgroups (clusters) of post COVID patients based on clinical symptoms, demographic characteristics, levels of fatigue and physical, cognitive and psychological functioning of the individuals.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The participant must report current persisting symptoms (such as brain fog, anxiety, shortness of breath, headaches but also others) and indicate on the Post COVID-19 Functional Status Scale that these have an impact on everyday functioning (grade 2, 3, and 4). These symptoms need to be present for more than two months.
- •Further inclusion criteria are:
- •Fatigue Severity Scale (FSS) score > 4
- •Aged over 18 years old
- •Willing to sign the digital informed consent
- •Dutch speaking and Dutch understanding
- •Be tested positive for COVID-19, i.e. by reverse transcription polymerase chain reaction (RT-PCR), computed tomography (CT) of the lungs, or symptom-based diagnosis by the general practitioner.
排除标准
- •Pregnant women
- •Pacemaker, defibrillator
- •Brain or nerve disorders
- •A copper spiral or recent bone fracture
结局指标
主要结局
Fatigue severity
时间窗: Day 1
Fatigue severity scale (FSS)
Psychological evaluation
时间窗: Day 1
Anxiety and depression Scale (HADS); MINI-S, MINI International Neuropsychiatric Interview - Simplified (Overbeek \& Schruers 2019)
Physical evaluation
时间窗: Day 1
Hand grip strength (Jamar hand dynamometer) \& Six Minute Walk Test (6MWT)
Cognitive evaluation
时间窗: Day 1
Multi-modal Evaluation of Sensory Sensitivity (MESSY); Montreal Cognitive Assessment (MoCA)
次要结局
未报告次要终点
研究者
Stef Feijen
Doctoral Assistant
Hasselt University