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Clinical Trials/NCT03474848
NCT03474848
Completed
Not Applicable

The Effects of Hand-Arm Bimanual Intensive Training (HABIT) in Hand Function and Daily Functioning of Children With Bilateral Cerebral Palsy: a Randomized Controlled Trial

Federal University of Minas Gerais0 sites40 target enrollmentJanuary 5, 2016
ConditionsCerebral Palsy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cerebral Palsy
Sponsor
Federal University of Minas Gerais
Enrollment
40
Primary Endpoint
Functional goals
Status
Completed
Last Updated
6 years ago

Overview

Brief Summary

Hand-Arm Bimanual Intensive Training (HABIT) has been shown to result in improvements in hand function and daily functioning of children with unilateral cerebral palsy (CP). Children with bilateral CP may also present difficulties to coordinate their hands to perform activities. Thus, HABIT may be a potential intervention for these individuals. We intend to examine the effects of HABIT on hand function and daily functioning of children with bilateral CP compared with conventional occupational therapy (OT). Our hypothesis is that children receiving HABIT will present larger improvements in manual dexterity and daily functioning as compared to conventional OT.

Detailed Description

Study Design: Randomized Controlled Trial. Study Participants \& Setting: Forty children with bilateral CP recruited from the Associação Mineira de Reabilitação, Belo Horizonte, Brazil. Procedures: After being included in the study, children will be randomly assigned to a intervention group (n=20) or a control group (n=20). Children in the intervention group will receive a 90-hour (6 hours/day; 5 days/week, 3 weeks) of Hand-Arm Bimanual Intensive Training (HABIT) while children in control group will maintain their usual frequency of Occupational Therapy (OT) sessions (45 minutes/session, twice a week, for 3 weeks), focusing on functional training, stretching and sensory stimulation. All participants will be assessed by an examiner blinded to group allocation before and after the intervention period, as well as 6 months after the intervention (follow-up). Statistical Analysis: A 2 (groups) x 3 (assessments) analysis of variance will test the effects of group, assessment and group x assessment interaction with a level of significance set at 0.05.

Registry
clinicaltrials.gov
Start Date
January 5, 2016
End Date
March 30, 2019
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Federal University of Minas Gerais
Responsible Party
Principal Investigator
Principal Investigator

MARINA B BRANDAO

Professor

Federal University of Minas Gerais

Eligibility Criteria

Inclusion Criteria

  • Medical diagnosis of bilateral CP;
  • Age between 4 and 17 years old;
  • Manual Ability Classification System (MACS) ranging from levels I to III;
  • Ability to understand verbal instructions.

Exclusion Criteria

  • Botulinum toxin or surgery in upper limbs in the previous 6 months of the study.

Outcomes

Primary Outcomes

Functional goals

Time Frame: 6 months

Canadian Occupational Performance Measure (COPM) - performance and satisfaction scales (each scale ranging 1-10; higher values, better outcomes)

Daily functioning

Time Frame: 6 months

Pediatric Evaluation Disability Inventory (PEDI) \[Scales: (1)self-care functional skills : ranging from 0-63; higher values, better outcomes; (2) caregiver assistance in self care: ranging from 0-40; higher values, better outcome\]

Secondary Outcomes

  • Manual dexterity(6 months)
  • Bimanual hand use(6 months)

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