Autologous Bone Marrow Cell Treatment in Patients With Peripheral Atherosclerosis

University of Naples1 site in 1 country20 target enrollmentApril 2005

ConditionsPeripheral Vascular Diseases

Overview

Phase: Phase 1
Intervention: Not specified
Conditions: Peripheral Vascular Diseases
Sponsor: University of Naples
Enrollment: 20
Locations: 1
Primary Endpoint: Clinical and instrumental indexes of functional impairment of peripheral atherosclerosis.
Last Updated: 20 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Implantation of bone marrow cells, including endothelial progenitor cells, into ischemic limbs has been shown to improve collateral vessel formation. In the present study the safety and feasibility of autologous blood mononuclear cells implantation will be investigated in patients with severe peripheral atherosclerosis.Twenty cases will be enrolled. Improvement in the ankle-brachial pressure index (ABI:>0.1), ischemic ulcers and angiography as well as laser doppler flow will be evaluated until six months.

Registry

clinicaltrials.gov

Start Date

April 2005

End Date

April 2006

Last Updated

20 years ago

Study Type

Interventional

Study Design

Single Group