The effect of sertreline and nortriptyline on quality of life in stroke patients
- Conditions
- Stroke.Cerebral infarction, unspecified
- Registration Number
- IRCT2016111530912N1
- Lead Sponsor
- Vice chancellor for research, Zanjan University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Stroke patients aged 50 to 70 years; The first episode of stroke; abcense of depressive symptom at the begining of study; No history of taking antidepressant before stroke; No contraindication for taking Sertraline and Nortriptyline; No history of aphasia
Exclusion criteria: Any history of CNS disorder e.g CVT, ALS, MS, Trauma; Any history of drug abuse; Ang contraindication for taking TCA e.g BPH, angle closure glaucoma, cardiovascular problem; Any history of liver and kidney problem
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Quality of life. Timepoint: Before intervention, 2 months after intervention and 4 months after intervention. Method of measurement: Nottingham Health Profile Questionnaire.
- Secondary Outcome Measures
Name Time Method Depression. Timepoint: At the begining of study, after taking drug treatment. Method of measurement: Beck Depression Inventory.