Project STRIDE2 - Seek/Test/Retain: PLWHA and Opioid Users in Washington, DC
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 159
- 试验地点
- 1
- 主要终点
- VL <400
研究概览
简要总结
STRIDE2 is a longitudinal, non-randomized study of individuals living with HIV who are dependent on opioids. This study is funded by the National Institute on Drug Abuse (R01DA030768, Altice, PI; Taxman & Lawson, Co-PIs) and is being conducted by George Mason University, Yale University, and Howard University.
详细描述
STRIDE2 will assist in identifying and monitoring individuals' HIV risk behaviors and provide resources to seek treatment for their HIV care and substance use. The goal of STRIDE2 is to examine if there are differences in HIV, drug use, and other outcomes between individuals receiving treatment versus individuals actively using, not actively using and not in treatment, and individuals on Methadone, Suboxone, or in some other treatment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •HIV+, confirmed by rapid HIV test
- •Meet DSM-IV criteria for opioid dependence
- •18 years or older
- •Have health insurance that is accepted at Lab Corp.
排除标准
- •Are <18 years old;
- •Are HIV negative;
- •Are Unable to communicate in English;
- •Are not able to provide informed consent;
- •Do not meet DSM-IV criteria for opioid dependence;
- •Plan to leave the DC area
研究组 & 干预措施
Buprenorphine
Participants are eligible for the study if they are 18 years of age or older, HIV+, meet DSM-IV criteria for opioid dependence, have health insurance accepted at Lab Corp, are able to read and understand English, and live in Washington, DC and plan to remain in DC. The intervention is to provide buprenorphine for 12 months for those who are interested in receiving it.
干预措施: buprenorphine (Drug)
结局指标
主要结局
VL <400
时间窗: 12 months
Blood test for HIV viral load
CD4+ cell count
时间窗: 12 months
Blood test for HIV CD4+ cell count
次要结局
- HIV risk behaviors(12 months)
- Retention in HIV care(12 months)
- Opioid use(12 months)
- Medically assisted therapy retention(12 months)