An evidence-based evaluation study of YuanJiang decoction in the treatment of symptomatic bradycardia

Xiyuan Hospital, China Academy of Chinese Medical Sciences0 个研究点开始时间: 待定最近更新: 2023年8月21日

适应症

试验速览

暂无简介。

•1. Patients who meet the diagnostic criteria for SND or AVB;
•2. Patients presenting with corresponding clinical symptoms such as dizziness, blurred vision, fatigue, palpitations, chest tightness, etc., and where the onset of symptoms is clearly related to bradycardia;
•3. Individuals who meet the indications for pacemaker implantation but have declined pacemaker treatment;
•4. Patients who conform to the criteria for Yang-deficiency and blood stasis syndrome in TCM;
•5. Age between 18 and 80 years old;
•6. Willingness to participate in the study and provide informed consent.

•1. Individuals with a maximum RR interval greater than 5 seconds or a minimum heart rate of 35 beats on a 24-hour ambulatory electrocardiogram;
•2. Patients with third-degree or high-degree atrioventricular block;
•3. Previous history of syncope due to bradycardia;
•4. Patients with severe cardiac, pulmonary, cerebral, or hematologic disorders, including but not limited to those conditions such as acute myocardial infarction within the last 2 weeks, unstable angina, ventricular tachycardia, ventricular fibrillation, and poorly controlled hypertension;
•5. Transient secondary bradyarrhythmia caused by medications;
•6. Athletes with low heart rate but normal sinus node function or athletes without arrhythmia-related symptoms
•7. Bradycardia caused by hypothyroidism;
•8. Pregnant or lactating women
•9. Patients with mental illness and substance abuse;
•10. Coagulation disorders;
•11. Allergic predisposition or known allergy to any of the 6 herbs used in the TJT;
•12. Participation in other clinical trials within the last month;
•13.Other condition that unable to meet the requirements of the study as judged by the researcher.

发起方