NCT01366625已完成不适用
Effects of Renal Denervation on Blood Pressure and Clinical Course of Obstructive Sleep Apnea in Patients With Resistant Hypertension
National Institute of Cardiology, Warsaw, Poland2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2011年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Blood Pressure Reduction
研究概览
简要总结
The purpose of this study is to investigate the clinical utility of renal denervation for the treatment of resistant hypertension coexisting with obstructive sleep apnea.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •>= 18 and =< 70 years of age.
- •systolic blood pressure >=140mmHg (office);
- •on 3 or more antihypertensive medications (including diuretic)
- •mean daytime systolic ABPM >= 135 mmHg
- •obstructive sleep apnea (AHI >=15 event/hour, indications for CPAP treatment)
排除标准
- •renal artery abnormalities
- •eGFR < 60mL/min
- •previous TIA, stroke, heart failure
- •Type 1 diabetes
- •ICD or pacemaker
结局指标
主要结局
Blood Pressure Reduction
时间窗: 3 months
次要结局
- Responses to renal denervation (e.g., blood pressure reduction, sleep apnea course, metabolic assessment, cardiac changes)(Through 1 year)
研究者
研究点 (2)
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