A TRIAL COMPARING EFFECTIVENESS OF TWO MANEUVERS FOR TREATMENT OF SUDDEN AND ABNORMALLY INCREASED HEART RATE

Not Applicable

• Conditions: Health Condition 1: I471- Supraventricular tachycardia

• Registration Number: CTRI/2021/01/030684
• Lead Sponsor: Department of Emergency Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1.Patients/Legally Authorized Representative(LAR) providing Informed consent

2. Diagnosis of supraventricular tachycardia (SVT; regular, narrow complex tachycardia with QRS duration <0.12 s on ECG with absent or overt p wave)

Exclusion Criteria

I. Unable or unwilling to give informed consent

II. Unstable condition (systolic blood pressure (BP) <90 mm Hg or any indication for immediate drug or direct current cardioversion)

III. Atrial fibrillation/atrial flutter/sinus tachycardia/MAT on ECG

IV. Systemic hypoperfusion

i. Altered mentation

ii. Chest pain (due to coronary ischemia)

iii. Dyspnea (due to pulmonary edema)

V. Severe hypertension (systolic BP >220 mm Hg or diastolic BP >120 mm Hg)

VI. Any contraindication to or inability to performing a Valsalva maneuver

VII. Contraindication or inability to lay flat and have legs lifted (or any reason identified by the patient as to why this maneuver would cause discomfort or pain)

VIII. Pregnancy

IX. Myocardial Infarction( <3 months)

X. Known case of glaucoma or retinopathy

XI. Previous inclusion in the study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cardioversion in Patients with supraventricular tachycardia(achievement of normal sinus rhythm on electrocardiography after standard/modified valsalva maneuver)Timepoint: 1 minute

Secondary Outcome Measures

Name	Time	Method
â??To compare sustained success rates at the third and fifth minute of application of the maneuver in each arm <br/ ><br>â?? Failure to revert SVT to a sinus rhythm, followed by: <br/ ><br>i) repeated attempts at Standard or Modified Valsalva Maneuver <br/ ><br>ii) pharmacological intervention; or <br/ ><br>iii) direct current countershock therapies. <br/ ><br>â?? To compare frequency and severity of adverse events resulting from application of maneuversTimepoint: 3, 5 minutes