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Diagnostic Evaluation of the Tear Film

Completed
Conditions
Dry Eye Syndromes
Interventions
Device: Tear Film Analyzer
Registration Number
NCT00761917
Lead Sponsor
TearScience, Inc.
Brief Summary

The objectives of this study are to assess for a difference between normal and dry eye subjects in tear film quality using a diagnostic interferometry device and to determine whether there are associations between tear film quality and dry eye symptoms and signs.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
229
Inclusion Criteria
  • Adults 18 year of age or older
  • Willing and able to comply with study exam procedure
Exclusion Criteria
  • Eyelid abnormality or ocular surface condition affecting ability to visualize tear film

  • Women who are pregnant or nursing

  • Any of the following conditions within specified timeframe prior to study participation:

    1. Instillation of eye drops
    2. Contact lens wear
    3. Use of oil-based facial cosmetics
    4. Swimming in chlorinated pool
    5. Eye examination procedures that may affect the tear film
    6. Participation in another ophthalmic clinical trial

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
2: Dry EyeTear Film AnalyzerSubjects with dry eye symptoms based on questionnaire.
1: NormalTear Film AnalyzerSubjects without dry eye symptoms based on questionnaire.
Primary Outcome Measures
NameTimeMethod
Tear film analysis of lipid layer qualityupon enrollment
Secondary Outcome Measures
NameTimeMethod
Dry Eye Symptomsupon enrollment
Corneal and Conjunctival Stainingupon enrollment
Tear Film Break-Up Timeupon enrollment
Meibomian Gland Assessmentupon enrollment
Schirmer Testupon enrollment
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