Impact of Body Mass Index on Positive End-expiratory Pressure Guided by Electrical Impedance Tomography for Patients Under General Anaesthesia

Completed

• Conditions: Positive Expiratory Pressure; Obesity; General Anesthetic
• Interventions: Other: regional ventilation monitoring

• Registration Number: NCT04439604
• Lead Sponsor: Centre Hospitalier Universitaire Dijon

Brief Summary

The induction of general anaesthesia is associated with a fall in lung volume due in particular to a decrease in muscle tone and the formation of denitrogenation atelectasis. Many recent studies insist on the need to apply a so-called "protective" strategy of intraoperative ventilation, which combines the use of recruitment manoeuvres, reduced tidal volume (Vt) (6-8ml/kg) and positive expiratory pressure (PEEP) to prevent these phenomena. However, the setting of PEEP remains debated and several authors agree on the need to individualize ventilatory parameters, particularly in obese patients, without describing the individualization tools.

In the ICU, it has been shown that electrical impedance tomography (EIT) can be used to individualise the PEEP level in a simple and non-invasive way. Therefore, we wish to determine whether the use of this technique during general anaesthesia allows for the individualization of PEEP, and whether the value determined is correlated with the body mass index (BMI).

Detailed Description

Not available

Study Timeline

• Study Start: 2018-10-06
• Primary Completion: 2019-07-06
• Study Completion: 2019-12-06
• Status Verified: 2020-06
• Study First Submitted: 2020-06-17
• Study First Submitted QC: 2020-06-17
• Study First Posted: 2020-06-19
• Last Update Submitted: 2020-06-19
• Last Update Posted: 2020-06-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 59

Inclusion Criteria

• Adult patient
• Patient who received general anesthesia with orotracheal intubation.
• Patient who has undergone surgery of the following types: : abdominal surgery by laparotomy or laparoscopy, emergency or scheduled

Exclusion Criteria

• NA

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
patient undergoing surgery under general anaesthesia	regional ventilation monitoring	-

Primary Outcome Measures

Name	Time	Method
electrical impedance tomography	Through study completion, an average of 1 year

Trial Locations

Locations (1)

Chu Dijon Bourgogne; 🇫🇷 Dijon, France