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The Effect of Whey Protein and Its Hydrolysate on Pre- and Post-Fixed Meal Glycemia and Insulin in Young Adults

Not Applicable
Completed
Conditions
Diabetes Prevention
Obesity Prevention
Interventions
Other: water control
Other: dietary intervention
Registration Number
NCT00988182
Lead Sponsor
University of Toronto
Brief Summary

The purpose of this study is to describe relationships among whey protein and its hydrolysate when consumed before a meal on pre- and post-fixed meal satiety, blood glucose and insulin in healthy young adults.

Detailed Description

A randomized, cross-over design study was conducted. Whey protein preloads (5-40 g) and hydrolysate whey protein (10 g) were provided in 300 ml water. At 30 min following consumption, subjects were fed a preset pizza meal (12 kcal/kg, experiment 2). Satiety, insulin and blood glucose were measured at baseline and selected intervals pre- and post-meal.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
22
Inclusion Criteria
  • normal body weight
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Exclusion Criteria
  • breakfast skippers
  • smokers
  • dieters or individuals with diabetes (fasting blood glucose ≥ 7.0 mmol/L) or other metabolic diseases
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Study & Design

Study Type
INTERVENTIONAL
Study Design
CROSSOVER
Arm && Interventions
GroupInterventionDescription
water controlwater control-
whey protein, 40gdietary intervention-
whey protein, 5gdietary intervention-
whey protein, 10gdietary intervention-
whey protein, 20gdietary intervention-
Primary Outcome Measures
NameTimeMethod
Blood glucose, Insulin, Subjective appetite0-170 min
Secondary Outcome Measures
NameTimeMethod
Physical comfort0-170 min

Trial Locations

Locations (1)

University of Toronto, Department of Nutritional Sciences

🇨🇦

Toronto, Ontario, Canada

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