Probiotic Intervention to reduce streptococcal disease burden in New Zealand Childre

Phase 3

Completed

• Conditions: S. pyogenes pharyngitis; Infection - Studies of infection and infectious agents

• Registration Number: ACTRN12615001076561
• Lead Sponsor: niversity of Otago, Wellington

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-10-13
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 1600

Inclusion Criteria

All children currently enrolled in Ministry of Health throat swabbing and treatment programme in East Porirua

Exclusion Criteria

1) Children with major heart disease as determined by study investigators. 2) Children with severe immune function impairment as determined by study investigators

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
proportion of children with S pyogenes positive sore throat during treatment period. Measured by standard micro throat swab for GAS[proportion during treatment period ie approx 145 days of three school terms]

Secondary Outcome Measures

Name	Time	Method
proportion of children with S. pyogenes carriage at end of trial in treatment versus placebo group. Measured by standard culture of a throat swab for GAS[end of treatment period. ie approx 145 days of treatment]