Preoperative Evaluation of IVC Collapsibility Index and Caval Aorta Index for Prediction of Hypotension After Induction of General Anesthesia in Patients Undergoing Craniotomy Surgeries
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Sensitivity of ultrasound guided Aorto-Caval index (IVC-AO)
研究概览
简要总结
This study aims to assess the accuracy, repeatability, and reproducibility of preoperative evaluation of Inferior Vena Cava (IVC) collapsibility index and caval aorta index for prediction of hypotension after induction of general anesthesia.
详细描述
Post- anesthesia hypotension is of common occurrence, and it hampers tissue perfusion. The magnitude of hypotension is determined by the preoperative volume status, which varies depending on American Society of Anesthesiologists (ASA) physical status, preoperative comorbidities, preoperative medications, and fasting.
General anesthesia causes significant alterations in hemodynamics, as both inhalational and intravenous anesthetics cause bradycardia, decrease in systemic vascular resistance and vasodilatation, and decrease in myocardial contractility, cardiac output and stroke volume, with the absence of surgical stimulus, making induction of anesthesia is the most crucial period at which hypotension occurs.
Due to different definitions of hypotension and diverse patient populations, the effect of volume preload on prevention of hypotension is still controversial. Many recommendations to identified sonographic determination of inferior vena cava (IVC) collapsibility index (IVCCI) as non-invasive, and easy technique for evaluating volume status. Recent guidelines from the American Society of Echocardiography support the general use of IVCCI in assessing volume status.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age from 18 to 40 years.
- •Both sexes.
- •Body Mass Index< 40 kg/m².
- •American Society of Anesthesiologists (ASA) physical status I, II.
- •Fasted according to the ASA guidelines: 2 hours for clear fluids, 6 hours after light meal, 8 hours after a full meal with high calorie or fat content.
- •Scheduled for elective craniotomy surgeries before induction of general anesthesia.
排除标准
- •Current or recent pregnancy (within 3 months).
- •Pre-existing cardiac disease or hypertension.
- •On medications affecting blood pressure [Beta-blockers (BBs) and calcium channel blockers (CCBs)] .
- •Refusing to undergo the study.
研究组 & 干预措施
Study group
Patients scheduled for elective craniotomy surgeries before induction of general anesthesia.
干预措施: Inferior vena cava collapsibility index (Other)
Study group
Patients scheduled for elective craniotomy surgeries before induction of general anesthesia.
干预措施: Caval Aorta Index (Other)
结局指标
主要结局
Sensitivity of ultrasound guided Aorto-Caval index (IVC-AO)
时间窗: 15 minutes post-induction of general anesthesia.
Sensitivity of ultrasound guided Aorto-Caval index (IVC-AO) to predict hypotension will be recorded.
次要结局
- Specificity of ultrasound guided Aorto-Caval index (IVC-AO)(15 minutes post-induction of general anesthesia.)
- Sensitivity of inferior vena cava (IVC) collapsibility index(15 minutes post-induction of general anesthesia.)
- Specificity of inferior vena cava (IVC) collapsibility index(15 minutes post-induction of general anesthesia.)
研究者
Verina Fares Zaref Bekheet
Assistant Lecturer of Anesthesia, Intensive Care and Pain Management, Ain Shams University, Cairo, Egypt
Ain Shams University