Modal Anatomy of the Ethmoid Bone

• Conditions: Anatomic Abnormality
• Interventions: Other: No intervention

• Registration Number: NCT04864730
• Lead Sponsor: Central Hospital, Nancy, France

Brief Summary

The creation of a 3D model of modal anatomy of the ethmoid could, like other parts of the body, improve anatomical, radiological and perhaps even surgical learning. Anatomical variations might constitute a "background noise" of the modal anatomy, which can be attenuated by multiplying the instances of acquisitions. The objective of this work is to establish modal anatomy of the ethmoid by the analysis of a large number of CT-scan acquisitions carried out in individuals with no acquired sinus pathology.

Detailed Description

Non-interventional descriptive research.

Sinus CTscans (period 2016-2019) will be reviewed from the PACS database of the CHRU of Nancy and selected in individuals without sinus pathology. All CT-scans will be fully anonymized. 26 landmarks will be pointed out to enable :

1. prior images alignment (centering on the median line, realignment rotations then resizing)

2. a mean and median calculation, allowing to establish a mean and median ethmoid model

3. calculation of standard deviations for each voxel The structures obtained in this way (bone, tissue or aerial) will be described anatomically.

Study Timeline

• Status Verified: 2020-09
• Study First Submitted: 2020-09-10
• Study First Submitted QC: 2021-04-25
• Study First Posted: 2021-04-29
• Last Update Submitted: 2021-06-19
• Last Update Posted: 2021-06-22
• Study Start: 2021-07-15
• Primary Completion: 2021-08-30
• Study Completion: 2021-09-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

All individuals (>18 years all) with a sinus CT scan available in the CHRU database

Exclusion Criteria

inflammatory sinus disease (eg. nasal polyposis, aspergilloma, ...) evolutive sinus tumor anatomical abnormality (e.g. post traumatic, prior sinus surgery, embryologic abnormality...)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
CT scans	No intervention	No intervention Data of voxels will be integrated to the final model

Primary Outcome Measures

Name	Time	Method
Descriptive study of the anatomy of the final 3D model	Through completion of the study: 1 month (The model will be available only at the end of the study, after implementation of all CT-scans)	Descriptive study; The study aims to produce the "modal" (generic) model from all the individual sub-models.; The structures obtained will be described anatomically by ENT experts: the created model will be described in comparison with anatomical data from literature: constant structures (e.g. middle turbinate, inferior turbinate, or orbital wall) will be listed and described (sites of insertion, direction, form), while variations in anatomical structures will be described through the variance (variances of voxels, pooled for each anatomical sub-site) (e.g. anterior ethmoid, sphenoid...). The heat map of voxels' variances will be superposed on the final model.; No scale/physiological parameter/questionnaire can be used for anatomical description of a single model. Therefore we don't really understand your remark "Please further specify the measurement that will be used (e.g., descriptive name of scale, physiological parameter, questionnaire) to assess this outcome measure."