Single and Double DNA Strand Breaks in Males With Unexplained Infertility Attending Fertility Treatment
Recruiting
- Conditions
- Infertility, Male
- Interventions
- Other: Sperm DNA Fragmentation
- Registration Number
- NCT05846256
- Lead Sponsor
- Peter Humaidan
- Brief Summary
The aim of this study is to investigate the extent of double-stranded DNA damage in sperm in men with unexplained infertility.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- Male
- Target Recruitment
- 125
Inclusion Criteria
- Unexplained infertile men who will undergo 1st or 2nd IVF treatment
- Age over 18 years
- Normal sperm parameters according to WHO criteria
- IVF treatment
Exclusion Criteria
- ICSI
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Infertile male Sperm DNA Fragmentation Men with unexplained infertility Donors (control) Sperm DNA Fragmentation Fertile sperm donors
- Primary Outcome Measures
Name Time Method The proportion of double-stranded DNA damage in sperm of men with unexplained infertility. 30-60 minutes Sperm DNA Fragmentation done with a Comet Assay analysis
- Secondary Outcome Measures
Name Time Method The proportion of single-stranded DNA damage in sperm of men with unexplained infertility 30-60 minutes Sperm DNA Fragmentation done with a Comet Assay analysis
Trial Locations
- Locations (1)
Fertility Clinic Regional Hospital Skive
🇩🇰Skive, Denmark