The Safety and Efficacy of Target-Controlled Infusion versus Intermittent Bolus of propofol for Sedation on Colonoscopy: A Controlled Randomized Study

Not Applicable

Recruiting

• Conditions: Colon polyps; Diverticulosis; Constipation; Irritable bowel syndrome.; K63.5; K59.0

• Registration Number: RBR-2dxshp
• Lead Sponsor: Associação Matogrossense de Combate ao Câncer

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-10-05
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

Patients with Physical Status I and II according American Society of Anesthesiologists ( ASA ); undergoing colonoscopy; aged 18 to 65 years; both gender and Body Mass Index ( BMI ) less than 30; accept to sign the Informed Consent

Exclusion Criteria

Patients with a history of allergy to any of the medicines; Body Mass Index greater than 30; refusal to sign the informed conset

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction of at least 25% of the number of interventions in the target-controlled infusion group. The following interventions were considered: Propofol dose adjustment by agitation and airway rescue maneuvers if oxygen saturation less than 92% that was verified by pulse oximete during the colonoscopy.

Secondary Outcome Measures

Name	Time	Method
Faster awakening in the target-controlled infusion group verified by the time between the end of the colonoscopy and the patient exhibiting OAAS score ( Observer Assessment of Alertness and Sedation ) greater than or equal to 3