minimal invasive treatment with radiofrequency ablation of breast carcinoma in elderly patients(>70 years) who are not or less fit for surgery

Completed

• Conditions: breastcancer; carcinoma of the breast; 10006291; 10006295

• Registration Number: NL-OMON31718
• Lead Sponsor: Jeroen Bosch Ziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

-breastcarcinoma (biopsy proven) with positive estrogenreceptorstatus
-tumor:maximal diameter is 2 cm
-due to comorbidity the tumor is not treatable with surgery or patient does not want to receive surgical treatment
-tumor can be localised using ultrasound
-patient is older than 70 years
-informed consent

Exclusion Criteria

-multiple carcinomas in the breast
-contra-indications for MR imaging
-hormone receptor negative tumors
-axillary lymph node metastasis
-metastasis in other organs

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>-Feasibility of RFA<br /><br>-Safety of RFA with registration of complications<br /><br>-Efficacy RFA with evaluating possible local tumor recurrence in the breast by<br /><br>MRI and core needle biopsies<br /><br>-Tumor recurrence (other organ than breast)<br /><br>-Patients experience (see also appendix 3 en 4)</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>n.a.</p><br>