The effects of amiodarone on serum apixaban level in Thai patients with atrial fibrillatio
Recruiting
- Conditions
- less numbers of participantsapixaban levelinteractionamiodarone
- Registration Number
- TCTR20201005003
- Lead Sponsor
- Faculty of Pharmacy, Silpakorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Age > 18 years old
AF patients used apixaban at least 7 days
AF patients used amiodarone at least 7 days
Good compliance 100 precent
Patients sign inform consent
Exclusion Criteria
Patients recieved enzyme inducer or inducer of CYP3A4, P-gp medication with apixaban that follow by ESC guideline 2018
Pregnancy and lactation patients
Psychritic patient
Patients were not sign inform consent
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Apixaban level at 0, 3, 8 hrs 0, 3, 8 hrs apixaban à¸à¸±à¸š anti-factor Xa activity
- Secondary Outcome Measures
Name Time Method correlation of apixaban and anti-factor Xa activity 0, 3, 8 hrs apixaban à¸à¸±à¸š anti-factor Xa activity