"Comparison of Spirulina Gels for Treating Stage II Grade B Periodontitis"
- Conditions
- Periodontitis Stage II
- Registration Number
- NCT06699654
- Lead Sponsor
- Kafrelsheikh University
- Brief Summary
This randomized controlled clinical study investigates the effectiveness of Spirulina gel and Spirulina nanoparticles gel in treating Stage II Grade B periodontitis. The research aims to compare the two formulations in terms of clinical, radiological, and biochemical outcomes, such as pocket depth reduction, alveolar bone density improvement, and inflammatory marker levels. The study seeks to provide insights into the potential of Spirulina-based therapies for enhancing periodontal health.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 15
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Reduction in Probing Pocket Depth (PPD) at baseline, 1 month , 3 months, 6 months The mean reduction in probing pocket depth in millimeters (mm) at periodontal sites treated with Spirulina gel and Spirulina nanoparticles gel.
- Secondary Outcome Measures
Name Time Method Radiographic Bone Density Improvement at baseline and after 6 months Changes in alveolar bone density measured using radiographic imaging techniques.
Biochemical Marker Levels Measured at baseline, 1 month ,3 months, and 6 months Reduction in inflammatory markers specifically Superoxide dismutase enzyme levels in gingival crevicular fluid.
Related Research Topics
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Trial Locations
- Locations (1)
Doctor Mohamed Samir Periodontal and Implantology Clinic
🇪🇬El-Sheikh Zayed City, Cairo, Egypt