NL-OMON50285已完成不适用
Ocular vestibular evoked myogenic potentials in patients with myasthenia gravis - oVEMPs in patients with myasthenia gravis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 102
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Cross-sectional study (objective 1)
- •Patients with MG:
- •* Patient is legally capable
- •* Definitive diagnosis of MG defined as the presence of a typical history and
- •at least one positive ancillary test,
- •including edrophonium testing, RNS, and serum autoantibodies
- •(anti-acetylcholine receptor [AChR], anti-muscle
- •specific tyrosine kinase [MuSK]).
- •Healthy controls:
- •* Healthy control is legally capable
- •* No diagnosis of MG
- •* Absence of disease that involves eye-muscle function or any other muscle
- •Controls with other neuromuscular diseases:
- •* Patient is legally capable
- •* No diagnosis of MG
- •* Definite diagnosis of other neuromuscular disease
- •Controls non-neuromuscular diseases that can cause diplopia:
- •* Patient is legally capable
- •* No diagnosis of MG
- •* No other neuromuscular disease
- •* Definite diagnosis that can cause diplopia
- •* Presence of diplopia
- •Longitudinal study (objective 2)
- •Patients with the clinical suspicion of MG:
- •* Patient is legally capable
- •* MG is in the differential diagnosis
- •* No definitive diagnosis of MG'
- •Neostigmine study (objective 3)
- •Patients who undergo an acetylcholinesterase inhibitor (neostigmine) test within
- •routine clinical care:
- •* Patient is legally capable
- •* MG is in the differential diagnosis
- •* Patient undergoes neostigmine test for diagnostic purposes
排除标准
- •A potential subject who meets any of the following criteria will be excluded
- •from participation in this study:, * Patients who are legally incapable
- •* Patients who are under the age of 16
- •* Patients with known vestibulo-cochlear disorders
研究者
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