The Ozone Olive Oil on healing of Acute Perianal Fissure
Phase 2
- Conditions
- Acute perianal fissure.Acute anal fissureK60.0
- Registration Number
- IRCT20190423043356N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients with acute perianal fissure
Age between 18-65
Undergoing medical treatment
Exclusion Criteria
Previous perianal surgery
Commodities like Diabetes, IBD, STD, TB
Anorectal cancers
Immunodeficiency diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The severity of pain. Timepoint: Weekly follow up till 2 months. Method of measurement: Physical examination by surgeon and VAS score.;Bleeding. Timepoint: Weekly follow up till 2 months. Method of measurement: Physical examination by surgeon.;Itching. Timepoint: Weekly follow up till 2 months. Method of measurement: Patient report in VAS scale.;Wound healing. Timepoint: Weekly follow up till 2 months. Method of measurement: Physical examination by surgeon.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie ozone therapy's efficacy in acute perianal fissure healing?
How does ozone olive oil compare to nitroglycerin or calcium channel blockers in treating acute anal fissures?
Are there specific biomarkers that predict response to ozone-based treatments in perianal fissure patients?
What are the potential adverse events associated with ozone olive oil application for acute anal fissures?
What combination therapies or alternative compounds show promise alongside ozone for K60.0 perianal fissures?