Prolactin Hormone in Oral Lichen Planus

Completed

• Conditions: Oral Lichen Planus

• Registration Number: NCT04785703
• Lead Sponsor: October University for Modern Sciences and Arts

Brief Summary

Oral lichen planus (OLP) is one of the most common mucosal diseases with autoimmune etio-pathogenesis with involvement of various cytokines similar to psoriasis.It generally occurs more commonly in females, in a ratio of 3:2. prolactin (PRL),It is a peptide hormone that has a role in autoimmune related diseases like systemic lupus erythematosus and , rheumatoid Artheritis. The role of PrL in OLP pathogenesis was never investigated.the aim of this study is to investigate the expression of PRL receptors in tissue biopsies of OLP patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-06-19
• Primary Completion: 2020-08-22
• Study Completion: 2020-12-10
• Status Verified: 2021-03
• Study First Submitted: 2021-03-03
• Study First Submitted QC: 2021-03-03
• Last Update Submitted: 2021-03-03
• Study First Posted: 2021-03-08
• Last Update Posted: 2021-03-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• patients with oral lichen planus
• systemically healthy

Exclusion Criteria

• oral lichenoid lesions

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
prolactin receptors expression in oral mucous membrane	24 hours	immuno-histochemistry

Trial Locations

Locations (1)

October University for modern sciences and arts; 🇪🇬 Giza, Egypt