NCT04785703已完成不适用
Prolactin Hormone in Oral Lichen Planus Tissue Samples
October University for Modern Sciences and Arts1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2020年6月19日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- prolactin receptors expression in oral mucous membrane
研究概览
简要总结
Oral lichen planus (OLP) is one of the most common mucosal diseases with autoimmune etio-pathogenesis with involvement of various cytokines similar to psoriasis.It generally occurs more commonly in females, in a ratio of 3:2. prolactin (PRL),It is a peptide hormone that has a role in autoimmune related diseases like systemic lupus erythematosus and , rheumatoid Artheritis. The role of PrL in OLP pathogenesis was never investigated.the aim of this study is to investigate the expression of PRL receptors in tissue biopsies of OLP patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with oral lichen planus
- •systemically healthy
排除标准
- •oral lichenoid lesions
结局指标
主要结局
prolactin receptors expression in oral mucous membrane
时间窗: 24 hours
immuno-histochemistry
次要结局
未报告次要终点
研究者
Naglaa Elwakeel
professor
October University for Modern Sciences and Arts
研究点 (1)
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