Does the Addition of Hydrogen Peroxide to Chlorhexidine Skin Prep to Treat P. Acnes in the Shoulder
Not Applicable
- Conditions
- Propionibacterium Infection
- Interventions
- Registration Number
- NCT03656588
- Lead Sponsor
- Rothman Institute Orthopaedics
- Brief Summary
This is a prospective, randomized controlled trial to evaluate the ability of hydrogen peroxide preparation in addition to chlorhexidine to decrease the colonization of Propionibacterium acnes(a bacteria commonly found in the dermis of the skin surrounding the shoulder in order to decrease postoperative joint infection.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Male
- Target Recruitment
- 100
Inclusion Criteria
- All male patients (>18) undergoing shoulder arthroscopy
Exclusion Criteria
-
Female patients
-
Patients with active acne
-
Patients who have taken antibiotics within a month of their surgery
-
Subjects allergic to any of the following agents:
o Benzoyl peroxide
-
Subjects with psoriatic/eczematous lesions on the shoulder girdle.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by a. Standard iodine scrub, 3% hydrogen peroxide prep, follow by ChloraPrep (2% chlorhexidine gluconate and 70% isopropyl alcohol - b. Iodine scrub and ChloraPrep alone Iodine scrub and ChloraPrep alone -
- Primary Outcome Measures
Name Time Method colonization of p.acnes in the dermis of the shoulder 14 days in culture number of colony forming units grown in bacterial culture
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Rothman Institute
🇺🇸Philadelphia, Pennsylvania, United States