The development of an asthma-tailored pulmonary rehabilitation programme for individuals with severe asthma

Not Applicable

Completed

• Conditions: Severe asthma; Respiratory; Asthma

• Registration Number: ISRCTN96143888
• Lead Sponsor: niversity Hospitals of Leicester NHS Trust (UK)

Brief Summary

2016 protocol in: http://www.ncbi.nlm.nih.gov/pubmed/27009149

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-01-30
• Study Completion: 2018-09-13
• Last Update Posted: 16 March 2020

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 273

Inclusion Criteria

Patients with severe asthma (defined as asthma which remains symptomatic at steps 4-5 of the British Thoracic Society asthma guidelines), despite management for >6 months in the Glenfield Difficult Asthma Clinic (DAC), will be recruited. All patients will have a thorough diagnostic work up and a treatment strategy targeting eosinophillic airway inflammation to optimise control; exercise-induced asthma is often a reflection of poor control.

Exclusion Criteria

1. Severe exacerbation within a month of entry
2. Inability to exercise e.g. due to significant musculoskeletal or neurological abnormalities

Study & Design

• Study Type: Interventional
• Study Design: Not specified