Personalise antidepressant treatment for unipolar depression combining individual choices, risks and big data

niversity of Oxford0 个研究点目标入组 504 人开始时间: 2022年11月7日最近更新: 2022年11月21日

适应症

试验速览

暂无简介。

•1. Participant is willing and able to give informed consent for participation in the trial
•2. Aged 18 -74 years
•3. Clinical diagnosis of depressive disorder and for whom an antidepressant is clinically indicated
•4. Participants willing to take antidepressant treatment, but have not been treated with antidepressants in the previous 4 weeks
•5. Willing to meet any clinical requirements related to taking a specific medication
•6. Able to read/understand and/or complete self-administered questionnaires online in English

•1. Prescribed any antidepressant in the preceding 4 weeks
•2. Current or historical diagnosis of ADHD, alcohol/substance use disorder, bipolar disorder, dementia, eating disorders, mania/hypomania, OCD, PTSD, psychosis/schizophrenia, treatment-resistant depression (having tried two or more antidepressants for the same depressive episode at adequate dose and time)
•3. Diagnosis of arrhythmias (including Q-T prolongation, heart block), recent MI, poorly controlled epilepsy, acute porphyrias
•4. Require urgent mental care or admission (including suicidal intent/plans)
•5. Concurrently enrolled in another investigational medicinal product (IMP) trial or an interventional trial about depression
•6. Participants who are currently pregnant, planning pregnancy or lactating
•7. Has a medical, social or other condition which, in the investigator’s opinion, may make the participant unable to comply with all the trial requirements (e.g., terminal illness – motor neuron disease)

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