ISRCTN82850103
Active, not recruiting
未知
Personalise antidepressant treatment for unipolar depression combining individual choices, risks and big data
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- nipolar depression
- Sponsor
- niversity of Oxford
- Enrollment
- 504
- Status
- Active, not recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Participant is willing and able to give informed consent for participation in the trial
- •2\. Aged 18 \-74 years
- •3\. Clinical diagnosis of depressive disorder and for whom an antidepressant is clinically indicated
- •4\. Participants willing to take antidepressant treatment, but have not been treated with antidepressants in the previous 4 weeks
- •5\. Willing to meet any clinical requirements related to taking a specific medication
- •6\. Able to read/understand and/or complete self\-administered questionnaires online in English
Exclusion Criteria
- •1\. Prescribed any antidepressant in the preceding 4 weeks
- •2\. Current or historical diagnosis of ADHD, alcohol/substance use disorder, bipolar disorder, dementia, eating disorders, mania/hypomania, OCD, PTSD, psychosis/schizophrenia, treatment\-resistant depression (having tried two or more antidepressants for the same depressive episode at adequate dose and time)
- •3\. Diagnosis of arrhythmias (including Q\-T prolongation, heart block), recent MI, poorly controlled epilepsy, acute porphyrias
- •4\. Require urgent mental care or admission (including suicidal intent/plans)
- •5\. Concurrently enrolled in another investigational medicinal product (IMP) trial or an interventional trial about depression
- •6\. Participants who are currently pregnant, planning pregnancy or lactating
- •7\. Has a medical, social or other condition which, in the investigator’s opinion, may make the participant unable to comply with all the trial requirements (e.g., terminal illness – motor neuron disease)
Outcomes
Primary Outcomes
Not specified
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