Development of a Breath Analysis Test for Disease Diagnosis and Prognosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- Mayo Clinic
- 入组人数
- 46
- 试验地点
- 1
- 主要终点
- Breath Volatile Organic Compound Profiles
研究概览
简要总结
The purpose of the study is to develop a clinical test based on breath analysis that can be used for disease diagnosis or prognosis.
详细描述
The study will seek to collect and analyze breath samples from a broad range of patients to develop reference ranges and to refine the testing methods. Protocols for breath sample collection and algorithms for analysis will be developed. Samples will be collected from normal volunteers, persons with documented liver disease, organ transplant or with known COVID-19 test results.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Able to provide informed consent
排除标准
- 未提供
研究组 & 干预措施
Normal
No known medical conditions
干预措施: Collection of breath sample (Diagnostic Test)
Liver Cirrhosis
Clinically diagnosed with cirrhosis
干预措施: Collection of breath sample (Diagnostic Test)
COVID-19 tested
Persons with known test results for COVID-19 RNA
干预措施: Collection of breath sample (Diagnostic Test)
Other
Persons with other medical diagnosis, no known liver disease, negative for COVID-19
干预措施: Collection of breath sample (Diagnostic Test)
结局指标
主要结局
Breath Volatile Organic Compound Profiles
时间窗: 1 day
Detection of profiles of volatile organic compounds present in exhaled breath. The values in the table represent the number of participants from whom a volatile organic compound profile was able to be detected.
次要结局
未报告次要终点